Flygut: an atlas of the Drosophila adult midgut

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Gene name Ddc
Flybase description The gene Dopa decarboxylase is referred to in FlyBase by the symbol Dmel\Ddc (CG10697, FBgn0000422).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.6233 3.3595 -14.54771 -18.3249 -16.000884 -23.0569 -3.62587 -2.914642
    Affimetrix absolute value 7.018 9.33 4.411 4.198 4.813 4.04 6.716 6.72
    Affymetric present call in "x" number of chips 3 3 1 0 0 1 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: aromatic-L-amino-acid decarboxylase activity.
There is experimental evidence that it is involved in the biological process: growth; dopamine biosynthetic process from tyrosine; serotonin biosynthetic process from tryptophan; thermosensory behavior; anesthesia-resistant memory; thermotaxis.
141 alleles are reported.
The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: organ system; adult segment; organ system subdivision; adult mesothoracic segment; sensillum; cuticle; sense organ; wing hair; eo support cell; adult cuticle.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Aromatic-L-amino-acid decarboxylase; Pyridoxal phosphate-dependent decarboxylase; Pyridoxal phosphate-dependent transferase, major domain; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; Pyridoxal phosphate-dependent transferase, major region, subdomain 2; Pyridoxal-phosphate binding site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.
Peak expression observed during late larval stages.
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