Flygut: an atlas of the Drosophila adult midgut

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Gene name Dhod
Flybase description The gene Dihydroorotate dehydrogenase is referred to in FlyBase by the symbol Dmel\Dhod (CG9741, FBgn0000447).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 1.2368 1.3591 -0.360156 -1.3824 -1.887502 -1.5892 -0.53048 -1.488109
    Affimetrix absolute value 8.714 8.057 8.141 7.921 7.855 7.894 8.303 7.703
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: dihydroorotate dehydrogenase activity.
Based on sequence similarity, it is predicted to be involved in the biological process: 'de novo' pyrimidine base biosynthetic process.
36 alleles are reported.
The phenotypes of these alleles are annotated with: eye; wing; arista; wing hair.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Aldolase-type TIM barrel; Dihydroorotate dehydrogenase, class 1/ 2; Dihydroorotate dehydrogenase, class 2; Dihydroorotate dehydrogenase, conserved site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed during late pupal stages, in adult male stages.
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