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Gene name | dib | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene disembodied is referred to in FlyBase by the symbol Dmel\dib (CG12028, FBgn0000449). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: ecdysteroid 22-hydroxylase activity. There is experimental evidence that it is involved in the biological process: central nervous system development; dorsal closure; ecdysone biosynthetic process; head involution; midgut development; chitin-based embryonic cuticle biosynthetic process. 24 alleles are reported. The phenotypes of these alleles are annotated with 20 unique terms, many of which group under: organ system; multicellular structure; cuticle; organ system subdivision; nervous system; primordium; non-connected developing system; integumentary system; cuticular specialization; multi-cell-component structure. It has one annotated transcript and one annotated polypeptide. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 00-06 hour embryonic stages. . |