Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Lar
Flybase description The gene Leukocyte-antigen-related-like is referred to in FlyBase by the symbol Dmel\Lar (CG10443, FBgn0000464).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -13.0076 -6.7285 -12.839187 -10.2386 -19.554611 -10.4391 -11.65377 -17.241438
    Affimetrix absolute value 4.707 4.872 4.528 5.046 4.501 5.208 5.03 4.174
    Affymetric present call in "x" number of chips 2 3 2 3 1 3 3 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein tyrosine phosphatase activity; SAM domain binding.
There is experimental evidence for 12 unique biological process terms, many of which group under: anatomical structure development; cellular component organization or biogenesis; locomotion; multicellular organismal reproductive process; macromolecule modification; biological regulation; taxis; compound eye photoreceptor development; cell adhesion; protein modification process; regulation of developmental process; cell projection organization; multicellular organism reproduction.
57 alleles are reported.
The phenotypes of these alleles are annotated with 22 unique terms, many of which group under: organ system subdivision; female germline cyst; embryonic/larval neuron; organ system; germarium; multi-cell-component structure; peripheral nervous system; egg; adult segment; nervous system.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: Fibronectin type III domain; Fibronectin, type III; Immunoglobulin I-set; Immunoglobulin subtype 2; Immunoglobulin-like; Immunoglobulin-like fold; Protein-tyrosine phosphatase, active site; Protein-tyrosine phosphatase, receptor/non-receptor type; Protein-tyrosine/Dual-specificity phosphatase.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 12-24 hour embryonic stages, at stages throughout the pupal period.
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