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Gene name | Lar | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Leukocyte-antigen-related-like is referred to in FlyBase by the symbol Dmel\Lar (CG10443, FBgn0000464). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein tyrosine phosphatase activity; SAM domain binding. There is experimental evidence for 12 unique biological process terms, many of which group under: anatomical structure development; cellular component organization or biogenesis; locomotion; multicellular organismal reproductive process; macromolecule modification; biological regulation; taxis; compound eye photoreceptor development; cell adhesion; protein modification process; regulation of developmental process; cell projection organization; multicellular organism reproduction. 57 alleles are reported. The phenotypes of these alleles are annotated with 22 unique terms, many of which group under: organ system subdivision; female germline cyst; embryonic/larval neuron; organ system; germarium; multi-cell-component structure; peripheral nervous system; egg; adult segment; nervous system. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: Fibronectin type III domain; Fibronectin, type III; Immunoglobulin I-set; Immunoglobulin subtype 2; Immunoglobulin-like; Immunoglobulin-like fold; Protein-tyrosine phosphatase, active site; Protein-tyrosine phosphatase, receptor/non-receptor type; Protein-tyrosine/Dual-specificity phosphatase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 12-24 hour embryonic stages, at stages throughout the pupal period. . |