Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name e
Flybase description The gene ebony is referred to in FlyBase by the symbol Dmel\e (CG3331, FBgn0000527).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -10.3969 -8.0002 -11.012736 -13.3681 -18.263468 -18.0194 -14.74688 -12.742261
    Affimetrix absolute value 5.057 4.631 4.735 4.648 4.573 4.393 4.676 4.613
    Affymetric present call in "x" number of chips 0 2 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: beta-alanyl-dopamine synthase activity.
There is experimental evidence that it is involved in the biological process: cuticle pigmentation; chitin-based cuticle tanning; regulation of adult chitin-containing cuticle pigmentation; dopamine metabolic process; negative regulation of melanin biosynthetic process; histamine metabolic process; amino acid adenylylation by nonribosomal peptide synthase.
55 alleles are reported.
The phenotypes of these alleles are annotated with: trident; retina; embryonic/larval spiracle; adult cuticle; mesothoracic tergum; wing; synaptic vesicle.
It has one annotated transcript and one annotated polypeptide.
Protein features are: AMP-binding, conserved site; AMP-dependent synthetase/ligase; Acyl carrier protein-like; Phosphopantetheine-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.
Peak expression observed during late larval stages, at stages throughout the pupal period.
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