Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name eag
Flybase description The gene ether a go-go is referred to in FlyBase by the symbol Dmel\eag (CG10952, FBgn0000535).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -25.4104 -18.8427 -22.181657 -25.4526 -35.470991 -35.8453 -29.92661 -24.952593
    Affimetrix absolute value 3.744 3.43 3.747 3.724 3.615 3.399 3.65 3.666
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: voltage-gated cation channel activity.
There is experimental evidence that it is involved in the biological process: perineurial glial growth; flight behavior; learning.
23 alleles are reported.
The phenotypes of these alleles are annotated with: leg; neuromuscular junction; synapse; adult brain.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Cyclic nucleotide-binding domain; Cyclic nucleotide-binding-like; Ion transport; PAC motif; PAS; PAS fold; PAS-associated, C-terminal; Potassium channel, voltage-dependent, EAG; Potassium channel, voltage-dependent, EAG/ELK/ERG; RmlC-like jelly roll fold.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed during late larval stages, during early pupal stages.
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