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Gene name | EcR | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Ecdysone receptor is referred to in FlyBase by the symbol Dmel\EcR (CG1765, FBgn0000546). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: ecdysteroid hormone receptor activity; protein binding; protein heterodimerization activity; repressing transcription factor binding. There is experimental evidence for 40 unique biological process terms, many of which group under: anatomical structure development; biological regulation; cellular process involved in reproduction; multicellular organismal reproductive process; organ development; cellular component organization or biogenesis; embryonic development via the syncytial blastoderm; central nervous system development; post-embryonic organ morphogenesis; determination of adult lifespan; neuron maturation; locomotory behavior; catabolic process; response to cocaine; ecdysis, chitin-based cuticle; prepupal development; memory. 140 alleles are reported. The phenotypes of these alleles are annotated with 58 unique terms, many of which group under: organ system; organ system subdivision; adult segment; cuticle; imaginal precursor; cephalopharyngeal skeleton; female germline cyst; portion of tissue; egg; extended germ band embryo; cytoplasmic part; spiracle; external compound sense organ; gland. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: Ecdysteroid receptor; Nuclear hormone receptor, ligand-binding; Nuclear hormone receptor, ligand-binding, core; Steroid hormone receptor; Zinc finger, NHR/GATA-type; Zinc finger, nuclear hormone receptor-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 06-18 hour embryonic stages, during late larval stages, during early pupal stages. . |