Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name emc
Flybase description The gene extra macrochaetae is referred to in FlyBase by the symbol Dmel\emc (CG1007, FBgn0000575).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 3.7572 5.9107 1.989409 3.6795 -0.330503 2.2886 1.86653 1.945637
    Affimetrix absolute value 10.316 10.167 9.157 10.26 8.752 9.756 9.401 9.129
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein heterodimerization activity.
There is experimental evidence for 20 unique biological process terms, many of which group under: anatomical structure development; organ morphogenesis; sensory organ development; biological regulation; post-embryonic appendage morphogenesis; embryonic development via the syncytial blastoderm; post-embryonic organ morphogenesis; cell-cell signaling; cellular process involved in reproduction; cell proliferation; compound eye cone cell differentiation; neuromuscular process; behavioral interaction between organisms; locomotion.
98 alleles are reported.
The phenotypes of these alleles are annotated with 42 unique terms, many of which group under: organ system subdivision; adult segment; primordium; external compound sense organ; organ system; female germline cyst; midgut constriction; adult mesothoracic segment; non-connected developing system; nervous system.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Helix-loop-helix DNA-binding; Helix-loop-helix DNA-binding domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed within 00-18 hour embryonic stages.
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