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Gene name | esc | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene extra sexcombs is referred to in FlyBase by the symbol Dmel\esc (CG14941, FBgn0000588). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: histone methyltransferase activity (H3-K27 specific); protein binding; histone methyltransferase activity. There is experimental evidence that it is involved in the biological process: gene silencing; histone methylation; histone H3-K27 methylation; dendrite morphogenesis; neuron development; muscle organ development; chromatin silencing. 59 alleles are reported. The phenotypes of these alleles are annotated with 35 unique terms, many of which group under: embryonic segment; embryonic abdomen; multicellular structure; thoracic segment; adult segment; organ system subdivision; abdominal segment 7; embryonic head; embryonic thoracic segment; embryonic abdominal segment 4; abdominal segment 10; antennal segment; midgut constriction. It has one annotated transcript and one annotated polypeptide. Protein features are: WD40 repeat; WD40 repeat 2; WD40 repeat, conserved site; WD40 repeat, subgroup; WD40 repeat-like-containing domain; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages. . |