Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name esc
Flybase description The gene extra sexcombs is referred to in FlyBase by the symbol Dmel\esc (CG14941, FBgn0000588).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -19.3371 -10.9981 -9.060119 -9.8491 -17.688629 -15.2034 -21.3089 -11.976403
    Affimetrix absolute value 4.146 4.192 5.001 5.094 4.622 4.638 4.137 4.7
    Affymetric present call in "x" number of chips 0 1 0 3 0 0 1 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: histone methyltransferase activity (H3-K27 specific); protein binding; histone methyltransferase activity.
There is experimental evidence that it is involved in the biological process: gene silencing; histone methylation; histone H3-K27 methylation; dendrite morphogenesis; neuron development; muscle organ development; chromatin silencing.
59 alleles are reported.
The phenotypes of these alleles are annotated with 35 unique terms, many of which group under: embryonic segment; embryonic abdomen; multicellular structure; thoracic segment; adult segment; organ system subdivision; abdominal segment 7; embryonic head; embryonic thoracic segment; embryonic abdominal segment 4; abdominal segment 10; antennal segment; midgut constriction.
It has one annotated transcript and one annotated polypeptide.
Protein features are: WD40 repeat; WD40 repeat 2; WD40 repeat, conserved site; WD40 repeat, subgroup; WD40 repeat-like-containing domain; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages.
.