Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name fj
Flybase description The gene four-jointed is referred to in FlyBase by the symbol Dmel\fj (CG10917, FBgn0000658).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -24.6273 -18.4306 -34.052675 -33.5644 -48.318834 -36.5533 -38.46698 -33.349037
    Affimetrix absolute value 3.792 3.417 3.128 3.32 3.188 3.39 3.285 3.186
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: Wnt-protein binding; protein kinase activity.
There is experimental evidence that it is involved in the biological process: establishment of imaginal disc-derived wing hair orientation; cell-cell signaling; imaginal disc-derived wing vein specification; establishment of epithelial cell apical/basal polarity; regulation of tube length, open tracheal system; imaginal disc growth; imaginal disc-derived leg joint morphogenesis; Wnt receptor signaling pathway, planar cell polarity pathway.
50 alleles are reported.
The phenotypes of these alleles are annotated with 29 unique terms, many of which group under: adult segment; organ system subdivision; adult mesothoracic segment; appendage segment; external compound sense organ; antennal segment; wing hair; imaginal precursor; peripheral nervous system; organ system.
It has one annotated transcript and one annotated polypeptide.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 06-12 hour embryonic stages.
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