Flygut: an atlas of the Drosophila adult midgut

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Gene name fkh
Flybase description The gene fork head is referred to in FlyBase by the symbol Dmel\fkh (CG10002, FBgn0000659).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.2279 1.0874 -5.615292 -3.7582 -7.705737 -3.0196 2.09825 -3.750879
    Affimetrix absolute value 8.114 7.738 5.772 6.497 5.919 7.01 9.603 6.406
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding.
There is experimental evidence that it is involved in the biological process: negative regulation of programmed cell death; anti-apoptosis; regulation of transcription from RNA polymerase II promoter; salivary gland development; ecdysone-mediated induction of salivary gland cell autophagic cell death; negative regulation of multicellular organism growth; salivary gland morphogenesis; negative regulation of cell growth.
30 alleles are reported.
The phenotypes of these alleles are annotated with 26 unique terms, many of which group under: organ system; organ system subdivision; primordium; nervous system; presumptive embryonic/larval nervous system; gland; late extended germ band embryo; hemocyte; extended germ band embryo; adult segment.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Fork-head N-terminal; Forkhead box protein, C-terminal; Transcription factor, fork head; Transcription factor, fork head, conserved site; Winged helix-turn-helix transcription repressor DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 06-12 hour embryonic stages.
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