Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name for
Flybase description The gene foraging is referred to in FlyBase by the symbol Dmel\for (CG10033, FBgn0000721).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 3.4467 3.6148 1.71005 2.8029 1.64392 2.0576 0.53315 1.939459
    Affimetrix absolute value 10.171 9.457 8.888 9.857 9.436 9.601 8.781 9.107
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: cGMP-dependent protein kinase activity.
There is experimental evidence that it is involved in the biological process: response to sucrose stimulus; larval feeding behavior; habituation; regulation of heart contraction; protein phosphorylation; short-term memory; regulation of response to food; long-term memory; larval locomotory behavior.
83 alleles are reported.
The phenotypes of these alleles are annotated with: adult Malpighian tubule; embryonic/larval tracheal system; mesothoracic tergum; crystal cell.
It has 11 annotated transcripts and 11 annotated polypeptides.
Protein features are: AGC-kinase, C-terminal; Cyclic nucleotide-binding domain; Cyclic nucleotide-binding, conserved site; Cyclic nucleotide-binding-like; Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; RmlC-like jelly roll fold; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain; cGMP-dependent kinase.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.
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