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Gene name | Fps85D | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Fps oncogene analog is referred to in FlyBase by the symbol Dmel\Fps85D (CG8874, FBgn0000723). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: protein tyrosine kinase activity. There is experimental evidence that it is involved in the biological process: dorsal closure, elongation of leading edge cells; dorsal closure; actin filament bundle assembly; axon guidance; photoreceptor cell morphogenesis; dorsal closure, amnioserosa morphology change. 19 alleles are reported. The phenotypes of these alleles are annotated with: dorsal closure embryo; amnioserosa; ventral midline. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Fps/Fes/Fer/CIP4 homology; Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; SH2 motif; Serine-threonine/tyrosine-protein kinase; Tyrosine-protein kinase, active site; Tyrosine-protein kinase, catalytic domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 06-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult male stages. . |