Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name fu
Flybase description The gene fused is referred to in FlyBase by the symbol Dmel\fu (CG6551, FBgn0001079).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -7.7088 -5.3949 -7.711618 -10.1683 -17.295964 -11.1402 -15.73003 -12.515124
    Affimetrix absolute value 5.47 5.197 5.238 5.057 4.697 5.096 4.627 4.627
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; protein serine/threonine kinase activity.
There is experimental evidence that it is involved in the biological process: smoothened signaling pathway; regulation of protein stability; positive regulation of transcription factor import into nucleus; segment polarity determination; germarium-derived egg chamber formation; positive regulation of hh target transcription factor activity.
158 alleles are reported.
The phenotypes of these alleles are annotated with 34 unique terms, many of which group under: organ system subdivision; adult segment; adult mesothoracic segment; female germline cyst; integumentary plate; organ system; non-connected developing system; presumptive embryonic/larval nervous system; mesothoracic tarsal bristle longitudinal row 3.
5; wing cell; appendage segment.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages.
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