Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Got1
Flybase description The gene Glutamate oxaloacetate transaminase 1 is referred to in FlyBase by the symbol Dmel\Got1 (CG8430, FBgn0001124).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 5.3442 5.0393 3.230093 2.2087 2.326434 4.9174 4.55115 3.135204
    Affimetrix absolute value 10.821 9.946 9.846 9.527 9.955 10.849 10.728 9.842
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: L-aspartate:2-oxoglutarate aminotransferase activity.
There is experimental evidence that it is involved in the biological process: glutamate biosynthetic process.
8 alleles are reported.
No phenotypic data is available.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Aminotransferase, class I/classII; Aspartate/other aminotransferase; Pyridoxal phosphate-dependent transferase, major domain; Pyridoxal phosphate-dependent transferase, major region, subdomain 1.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.
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