Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name gt
Flybase description The gene giant is referred to in FlyBase by the symbol Dmel\gt (CG7952, FBgn0001150).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -48.9086 -27.2851 -35.314316 -37.6889 -66.444008 -55.5654 -48.91177 -42.560202
    Affimetrix absolute value 2.805 2.893 3.053 3.152 2.715 2.766 2.947 2.886
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding.
There is experimental evidence that it is involved in the biological process: torso signaling pathway; terminal region determination; specification of segmental identity, labial segment; ring gland development; axon guidance; regulation of gene expression; regulation of cell size; negative regulation of multicellular organism growth; phagocytosis, engulfment.
86 alleles are reported.
The phenotypes of these alleles are annotated with 34 unique terms, many of which group under: organ system; abdominal segment 7; abdominal ventral denticle belt; embryonic segment; thoracic segment; embryonic abdomen; organ system subdivision; larval abdominal segment; multicellular structure; cephalopharyngeal skeleton; external compound sense organ; late extended germ band embryo.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Basic leucine zipper; Basic-leucine zipper (bZIP) transcription factor.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 00-06 hour embryonic stages.
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