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Gene name | h | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene hairy is referred to in FlyBase by the symbol Dmel\h (CG6494, FBgn0001168). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; RNA polymerase II core promoter proximal region sequence-specific DNA binding; protein binding; E-box binding. There is experimental evidence that it is involved in the biological process: response to hypoxia; tube morphogenesis; regulation of cellular metabolic process; negative regulation of transcription from RNA polymerase II promoter; cell morphogenesis; open tracheal system development; negative regulation of transcription, DNA-dependent; salivary gland morphogenesis. 200 alleles are reported. The phenotypes of these alleles are annotated with 51 unique terms, many of which group under: adult segment; abdominal ventral denticle belt; organ system subdivision; larval abdominal segment; organ system; adult mesothoracic segment; larval abdominal segment 8; somatic cell; prothoracic segment; larval abdominal segment 5. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Helix-loop-helix DNA-binding; Helix-loop-helix DNA-binding domain; Orange; Orange subgroup. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-06 and 18-24 hour embryonic stages. . |