Flygut: an atlas of the Drosophila adult midgut

 Mouche Logo lab lemaitre Bbcf logo
Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name hb
Flybase description The gene hunchback is referred to in FlyBase by the symbol Dmel\hb (CG9786, FBgn0001180).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -8.3649 -17.8658 -27.395298 -23.0191 -47.234713 -31.2432 -21.814 -25.964632
    Affimetrix absolute value 5.347 3.48 3.431 3.868 3.23 3.631 4.111 3.596
    Affymetric present call in "x" number of chips 3 0 0 0 0 0 3 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding; DNA binding.
There is experimental evidence that it is involved in the biological process: torso signaling pathway; terminal region determination; neuroblast fate determination; positive regulation of transcription, DNA-dependent.
124 alleles are reported.
The phenotypes of these alleles are annotated with 72 unique terms, many of which group under: organ system subdivision; thoracic segment; embryonic segment; cephalopharyngeal skeleton; embryonic/larval neuron; organ system; nervous system; peripheral nervous system; embryonic abdomen; primordium; prothoracic segment.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Zinc finger, C2H2; Zinc finger, C2H2-like; Zinc finger, C2H2-type/integrase, DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.
Peak expression observed within 00-06 hour embryonic stages.
.