Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Hsf
Flybase description The gene Heat shock factor is referred to in FlyBase by the symbol Dmel\Hsf (CG5748, FBgn0001222).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.1501 1.6675 -0.406648 -1.3426 -1.761148 -1.3986 -0.55051 -1.461358
    Affimetrix absolute value 8.218 8.332 8.081 7.971 7.95 8.08 8.286 7.766
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: sequence-specific DNA binding transcription factor activity; DNA binding.
There is experimental evidence that it is involved in the biological process: defense response to fungus; positive regulation of transcription from RNA polymerase II promoter; defense response to bacterium; response to methotrexate; response to heat; neurogenesis.
89 alleles are reported.
The phenotypes of these alleles are annotated with: polytene chromosome; egg chamber; nurse cell.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Heat shock factor (HSF)-type, DNA-binding; Vertebrate heat shock transcription factor; Winged helix-turn-helix transcription repressor DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages, during late pupal stages, in adult female stages.
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