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Gene name | hth | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene homothorax is referred to in FlyBase by the symbol Dmel\hth (CG17117, FBgn0001235). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: sequence-specific enhancer binding RNA polymerase II transcription factor activity; DNA binding. There is experimental evidence that it is involved in the biological process: positive regulation of transcription from RNA polymerase II promoter; compound eye development; specification of segmental identity, antennal segment; specification of segmental identity, head; segmentation; compound eye photoreceptor fate commitment; brain development; imaginal disc-derived wing morphogenesis; haltere morphogenesis; imaginal disc-derived leg morphogenesis. 70 alleles are reported. The phenotypes of these alleles are annotated with 64 unique terms, many of which group under: organ system subdivision; adult segment; external compound sense organ; abdominal lateral pentascolopidial chordotonal organ lch5; thoracic segment; embryonic segment; antennal segment; appendage segment; cuticle; adult mesothoracic segment. It has 8 annotated transcripts and 8 annotated polypeptides. Protein features are: Homeobox; Homeobox KN domain; Homeodomain-like; Homeodomain-related. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages. . |