Flygut: an atlas of the Drosophila adult midgut

 Mouche Logo lab lemaitre Bbcf logo
Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Idh
Flybase description The gene Isocitrate dehydrogenase is referred to in FlyBase by the symbol Dmel\Idh (CG7176, FBgn0001248).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 18.6222 27.1822 22.936912 7.6757 6.336484 11.1623 10.44029 14.697186
    Affimetrix absolute value 12.627 12.37 12.675 11.321 11.4 12.034 11.912 12.042
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: isocitrate dehydrogenase (NADP+) activity.
Based on sequence similarity, it is predicted to be involved in the biological process: glyoxylate cycle; tricarboxylic acid cycle.
20 alleles are reported.
The phenotype of these alleles is annotated with: trichogen cell.
It has 9 annotated transcripts and 9 annotated polypeptides.
Protein features are: Isocitrate dehydrogenase NADP-dependent, eukaryotic-type; Isocitrate/isopropylmalate dehydrogenase, conserved site; Isopropylmalate dehydrogenase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression.
Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.
.