Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name inv
Flybase description The gene invected is referred to in FlyBase by the symbol Dmel\inv (CG17835, FBgn0001269).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -28.5607 -17.1857 -21.04497 -31.4764 -35.968265 -34.8783 -33.18251 -26.682166
    Affimetrix absolute value 3.575 3.524 3.799 3.432 3.59 3.455 3.501 3.538
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: sequence-specific DNA binding transcription factor activity; transcription regulatory region sequence-specific DNA binding.
There is experimental evidence that it is involved in the biological process: neuroblast fate determination; compartment pattern formation.
37 alleles are reported.
The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system; organ system subdivision; adult segment; adult mesothoracic segment; thoracic segment; non-connected developing system; embryonic hindgut; cuticle; multi-cell-component structure; nervous system; adult; developing material anatomical entity.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Helix-turn-helix motif, lambda-like repressor; Homeobox; Homeobox engrailed; Homeobox engrailed, C-terminal; Homeobox engrailed-type, conserved site; Homeobox, conserved site; Homeobox, eukaryotic; Homeodomain-like; Homeodomain-related.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages.
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