Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name klar
Flybase description The gene klarsicht is referred to in FlyBase by the symbol Dmel\klar (CG17046, FBgn0001316).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.1178 1.6365 1.553429 -1.2296 -1.688394 -1.467 -2.24119 -0.585981
    Affimetrix absolute value 7.332 8.312 8.793 8.114 8.018 8.016 7.429 7.964
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: lipid particle transport along microtubule; tube morphogenesis; compound eye photoreceptor development; lipid transport; cellular membrane organization; nuclear migration; lumen formation, open tracheal system; compound eye morphogenesis.
85 alleles are reported.
The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: external compound sense organ; organ system subdivision; peripheral nervous system; nervous system; rhabdomere; egg; imaginal precursor; cytoplasmic part; embryonic foregut; cell part.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Klarsicht/ANC-1/syne-1 homology.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 12-24 hour embryonic stages, during late pupal stages.
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