Home | Overview of gut regions | Anatomy | Histology | Transgene expression mapping | Gene expression |
Search expression data by gene: |
Gene name | kn | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene knot is referred to in FlyBase by the symbol Dmel\kn (CG10197, FBgn0001319). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
|
||||||||||||||||||||||||||||||||||||
Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
||||||||||||||||||||||||||||||||||||
Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function: sequence-specific DNA binding transcription factor activity. There is experimental evidence that it is involved in the biological process: innate immune response; response to symbiont; regulation of transcription, DNA-dependent; specification of segmental identity, intercalary segment; head segmentation; dendrite morphogenesis; regulation of lamellocyte differentiation; embryonic development via the syncytial blastoderm; imaginal disc-derived wing vein specification. 25 alleles are reported. The phenotypes of these alleles are annotated with 42 unique terms, many of which group under: adult segment; hypodermal muscle of larval abdomen; organ system subdivision; organ system; adult mesothoracic segment; A1-7 oblique muscle; cephalopharyngeal skeleton; peripheral nervous system; larval abdominal segment 5; nervous system. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Cell surface receptor IPT/TIG; Helix-loop-helix DNA-binding domain; Immunoglobulin E-set; Immunoglobulin-like fold; Transcription factor COE; Transcription factor COE, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed at stages throughout embryogenesis. . |