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Gene name | kni | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene knirps is referred to in FlyBase by the symbol Dmel\kni (CG4717, FBgn0001320). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: sequence-specific DNA binding transcription factor activity. There is experimental evidence that it is involved in the biological process: dendrite morphogenesis; regulation of mitosis; muscle organ development; epidermis development. 108 alleles are reported. The phenotypes of these alleles are annotated with 30 unique terms, many of which group under: embryonic abdomen; embryonic segment; multicellular structure; adult segment; organ system; organ system subdivision; abdominal segment 7; thoracic segment; late extended germ band embryo; embryonic abdominal segment 4; dorsal trunk primordium; dorsal branch primordium; embryonic/larval hemocoel. It has one annotated transcript and one annotated polypeptide. Protein features are: Nuclear hormone receptor, ligand-binding; Zinc finger, NHR/GATA-type; Zinc finger, nuclear hormone receptor-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages. . |