Flygut: an atlas of the Drosophila adult midgut

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Gene name knk
Flybase description The gene knickkopf is referred to in FlyBase by the symbol Dmel\knk (CG6217, FBgn0001321).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -8.1335 -5.9424 -21.486263 -21.5314 -33.991304 -31.2429 -0.44543 -16.100756
    Affimetrix absolute value 5.432 5.071 3.786 3.963 3.697 3.609 8.409 4.252
    Affymetric present call in "x" number of chips 3 3 0 0 0 1 3 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
There is experimental evidence that it is involved in the biological process: torso signaling pathway; terminal region determination; regulation of tube diameter, open tracheal system; chitin biosynthetic process; regulation of tube size, open tracheal system; regulation of tube architecture, open tracheal system; embryonic epithelial tube formation; open tracheal system development; chitin-based embryonic cuticle biosynthetic process; cuticle chitin biosynthetic process.
17 alleles are reported.
The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system; cuticle; embryonic/larval tracheal system; integumentary system; tracheal system; cephalopharyngeal skeleton; multicellular structure; portion of tissue; cuticular specialization; non-connected developing system.
It has one annotated transcript and one annotated polypeptide.
Protein features are: DM13 domain; DOMON domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed at stages throughout the pupal period.
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