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| Gene name | kto | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene kohtalo is referred to in FlyBase by the symbol Dmel\kto (CG8491, FBgn0001324). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding; RNA polymerase II transcription cofactor activity. There is experimental evidence that it is involved in the biological process: bristle development; positive regulation of Wnt receptor signaling pathway; compound eye development; sex comb development; regulation of transcription from RNA polymerase II promoter; leg segmentation. 22 alleles are reported. The phenotypes of these alleles are annotated with: wing margin; eye disc; trichogen cell; antennal disc; photoreceptor cell; heart primordium; mesothoracic tergum. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Mediator complex, subunit Med12; Mediator complex, subunit Med12, LCEWAV-domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages, during early pupal stages. . |
