Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Kr
Flybase description The gene Kruppel is referred to in FlyBase by the symbol Dmel\Kr (CG3340, FBgn0001325).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -64.2408 -41.469 -53.542172 -64.31 -85.062883 -73.2485 -76.31625 -57.729746
    Affimetrix absolute value 2.41 2.255 2.441 2.388 2.353 2.367 2.299 2.419
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding; DNA binding.
There is experimental evidence that it is involved in the biological process: wing disc development; neuroblast fate determination; axon guidance; compound eye development; chromatin silencing.
96 alleles are reported.
The phenotypes of these alleles are annotated with 66 unique terms, many of which group under: organ system; hypodermal muscle of larval abdomen; embryonic segment; thoracic segment; organ system subdivision; embryonic abdomen; embryonic/larval neuron; abdominal ventral denticle belt; primordium; embryonic/larval excretory system.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Zinc finger, C2H2; Zinc finger, C2H2-like; Zinc finger, C2H2-type/integrase, DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression.
Peak expression observed within 00-12 hour embryonic stages.
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