Flygut: an atlas of the Drosophila adult midgut

 Mouche Logo lab lemaitre Bbcf logo
Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name dlg1
Flybase description The gene discs large 1 is referred to in FlyBase by the symbol Dmel\dlg1 (CG1725, FBgn0001624).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.3892 -2.9858 -7.049035 -3.3625 -11.525414 -4.7678 -1.87614 -7.295326
    Affimetrix absolute value 7.155 6.041 5.39 6.666 5.299 6.31 7.664 5.47
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence for 16 unique biological process terms, many of which group under: anatomical structure development; localization; cellular component organization or biogenesis; macromolecule localization; mating; protein localization; morphogenesis of follicular epithelium; behavioral interaction between organisms; multicellular organismal reproductive process; synaptic transmission; locomotory behavior; establishment or maintenance of polarity of follicular epithelium; locomotion.
99 alleles are reported.
The phenotypes of these alleles are annotated with 35 unique terms, many of which group under: organ system subdivision; nervous system; organ system; multi-cell-component structure; adult segment; presumptive embryonic/larval nervous system; imaginal precursor; female germline cyst; plasma membrane part; cuticle.
It has 17 annotated transcripts and 17 annotated polypeptides.
Protein features are: Guanylate kinase; Guanylate kinase, conserved site; Guanylate kinase/L-type calcium channel; L27; L27-1; PDZ/DHR/GLGF; Src homology-3 domain; Variant SH3.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in stages of adults of both sexes.
.