Flygut: an atlas of the Drosophila adult midgut

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Gene name Sos
Flybase description The gene Son of sevenless is referred to in FlyBase by the symbol Dmel\Sos (CG7793, FBgn0001965).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -14.1768 -3.697 -7.988657 -7.5404 -16.52245 -10.3716 -11.84194 -14.716173
    Affimetrix absolute value 4.588 5.747 5.223 5.484 4.778 5.203 5.038 4.41
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: regulation of cell shape; negative regulation of S phase of mitotic cell cycle; tracheal outgrowth, open tracheal system; actin filament organization.
93 alleles are reported.
The phenotypes of these alleles are annotated with 33 unique terms, many of which group under: organ system subdivision; external compound sense organ; larval abdominal segment; abdominal lateral pentascolopidial chordotonal organ lch5; nervous system; peripheral nervous system; embryonic/larval neuron; larval abdominal segment 5; adult segment; abdominal segment 7; multi-cell-component structure.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Dbl homology (DH) domain; Guanine-nucleotide dissociation stimulator CDC25; Histone core; Histone-fold; Pleckstrin homology domain; Pleckstrin homology-type; Ras GTP exchange factor, son of sevenless; Ras guanine nucleotide exchange factor; Ras guanine nucleotide exchange factor, domain; Ras guanine-nucleotide exchange factor, conserved site; Ras-like guanine nucleotide exchange factor, N-terminal.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages, during early pupal stages, in adult female stages.
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