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Gene name | Ca-alpha1D | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Ca2+-channel protein α |
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Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: voltage-gated calcium channel activity. There is experimental evidence that it is involved in the biological process: epithelial fluid transport. 12 alleles are reported. The phenotypes of these alleles are annotated with: cephalopharyngeal skeleton; NMJ bouton; neuromuscular junction; embryonic/larval tracheal system; longitudinal connective; wing; abdominal segmental nerve. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Ion transport; Voltage-dependent calcium channel, L-type, alpha-1 subunit; Voltage-dependent calcium channel, alpha-1 subunit; Voltage-dependent calcium channel, alpha-1 subunit, IQ domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed during late pupal stages. . |