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Gene name | l(2)gl | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene lethal (2) giant larvae is referred to in FlyBase by the symbol Dmel\l(2)gl (CG2671, FBgn0002121). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: myosin II binding; myosin binding. There is experimental evidence for 22 unique biological process terms, many of which group under: anatomical structure development; localization; biological regulation; cellular component organization or biogenesis; cellular process involved in reproduction; gland morphogenesis; macromolecule localization; morphogenesis of follicular epithelium; larval chitin-based cuticle development; establishment or maintenance of polarity of follicular epithelium. 99 alleles are reported. The phenotypes of these alleles are annotated with 48 unique terms, many of which group under: organ system subdivision; organ system; adult segment; portion of tissue; female germline cyst; gland; imaginal precursor; larval thorax; adult mesothoracic segment; eo support cell; dorsal thoracic disc. It has 10 annotated transcripts and 10 annotated polypeptides. Protein features are: Lethal giant larvae (Lgl)-like, C-terminal; Lethal giant larvae homologue 2; Lethal(2) giant larvae protein; WD40 repeat; WD40 repeat-like-containing domain; WD40/YVTN repeat-like-containing domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis. . |