Flygut: an atlas of the Drosophila adult midgut

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Gene name hyd
Flybase description The gene hyperplastic discs is referred to in FlyBase by the symbol Dmel\hyd (CG9484, FBgn0002431).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.2176 1.6005 -0.665817 0.3715 -2.985185 -1.1263 1.47313 -2.590496
    Affimetrix absolute value 8.128 8.283 7.807 8.439 7.252 8.391 9.079 7.077
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: ubiquitin-protein ligase activity.
There is experimental evidence that it is involved in the biological process: male meiosis cytokinesis; spermatid nucleus differentiation; female gonad development; imaginal disc development; eye-antennal disc morphogenesis; imaginal disc growth; spermatogenesis.
43 alleles are reported.
The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system; multicellular structure; organelle; dorsal thoracic disc; imaginal precursor; thoracic segment; anatomical structure; larval thorax; organ system subdivision; spermatocyte; elongation stage spermatid; cytoplasmic part; nucleus.
It has one annotated transcript and one annotated polypeptide.
Protein features are: HECT; Polyadenylate-binding protein/Hyperplastic disc protein; Regulator of chromosome condensation/beta-lactamase-inhibitor protein II; Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote; Zinc finger, N-recognin; Zinc finger, N-recognin, metazoa.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.
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