Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name sti
Flybase description The gene sticky is referred to in FlyBase by the symbol Dmel\sti (CG10522, FBgn0002466).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -52.7897 -28.6708 -37.767564 -37.8565 -46.134167 -34.2127 -63.75648 -38.922763
    Affimetrix absolute value 2.701 2.78 2.938 3.16 3.256 3.498 2.568 3.014
    Affymetric present call in "x" number of chips 0 0 0 0 0 3 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: diacylglycerol binding; protein serine/threonine kinase activity.
There is experimental evidence that it is involved in the biological process: cytokinesis after mitosis; chromatin organization; cytokinesis; cytokinesis, completion of separation; cytokinesis, actomyosin contractile ring assembly; regulation of actin cytoskeleton organization.
20 alleles are reported.
The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system; organ system subdivision; external compound sense organ; organelle; somatic cell; compound cell cluster organ; nervous system; protein complex; presumptive embryonic/larval nervous system; spermatocyte; imaginal precursor; female germline cyst; nucleus.
It has one annotated transcript and one annotated polypeptide.
Protein features are: AGC-kinase, C-terminal; Citron-like; Protein kinase C-like, phorbol ester/diacylglycerol binding; Protein kinase, ATP binding site; Protein kinase, C-terminal; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression.
Peak expression observed within 00-06 hour embryonic stages.
.