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| Gene name | lab | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene labial is referred to in FlyBase by the symbol Dmel\lab (CG1264, FBgn0002522). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity. There is experimental evidence that it is involved in the biological process: embryo development; brain development; brain segmentation. 37 alleles are reported. The phenotypes of these alleles are annotated with 21 unique terms, many of which group under: organ system subdivision; organ system; nervous system; adult segment; presumptive embryonic/larval nervous system; cephalopharyngeal skeleton; commissure; multi-cell-component structure; portion of tissue; podocyte; frontal connective; antennal segment. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Homeobox; Homeobox, conserved site; Homeobox, eukaryotic; Homeodomain-like; Homeodomain-related. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages, during early larval stages. . |
