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Gene name | lea | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene leak is referred to in FlyBase by the symbol Dmel\lea (CG5481, FBgn0002543). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function: axon guidance receptor activity; receptor activity. There is experimental evidence for 12 unique biological process terms, many of which group under: anatomical structure development; organ development; central nervous system development; biological regulation; organ morphogenesis; locomotion; cellular component organization or biogenesis; multicellular organismal process; regulation of biological process; embryonic heart tube development; ventral cord development; localization; regulation of multicellular organismal development. 50 alleles are reported. The phenotypes of these alleles are annotated with 43 unique terms, many of which group under: organ system subdivision; multi-cell-component structure; nervous system; embryonic/larval neuron; adult segment; hypodermal muscle of larval abdomen; cephalopharyngeal skeleton; commissure; A1-7 transverse muscle; primordium. It has one annotated transcript and one annotated polypeptide. Protein features are: Fibronectin type III domain; Fibronectin, type III; Immunoglobulin I-set; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like; Immunoglobulin-like fold. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed within 00-12 hour embryonic stages. . |