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Gene name | mam | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene mastermind is referred to in FlyBase by the symbol Dmel\mam (CG8118, FBgn0002643). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: transcription coactivator activity. There is experimental evidence that it is involved in the biological process: germ-line stem cell maintenance; heart morphogenesis; apposition of dorsal and ventral imaginal disc-derived wing surfaces; mesodermal cell fate determination; imaginal disc-derived wing margin morphogenesis; somatic stem cell maintenance; bristle morphogenesis; imaginal disc-derived wing morphogenesis; asymmetric cell division. 194 alleles are reported. The phenotypes of these alleles are annotated with 73 unique terms, many of which group under: organ system subdivision; synaptic neuropil subdomain; antennal segment; adult segment; embryonic/larval neuron; adult mesothoracic segment; presumptive embryonic/larval nervous system; peripheral nervous system; embryonic/larval glial cell; primordium. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Neurogenic mastermind-like, N-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period. . |