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| Gene name | twe | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene twine is referred to in FlyBase by the symbol Dmel\twe (CG4965, FBgn0002673). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: protein tyrosine phosphatase activity. There is experimental evidence that it is involved in the biological process: regulation of meiotic cell cycle; spindle assembly involved in male meiosis; pole cell formation; regulation of syncytial blastoderm mitotic cell cycle; meiotic nuclear envelope disassembly; embryo development; male meiosis; cellularization; spindle assembly involved in female meiosis; spermatogenesis. 17 alleles are reported. The phenotypes of these alleles are annotated with: yolk; trichogen cell; oocyte; spindle; tormogen cell; spermatocyte; oocyte nucleus. It has one annotated transcript and one annotated polypeptide. Protein features are: M-phase inducer phosphatase; Rhodanese-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages. . |
