Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Met
Flybase description The gene Methoprene-tolerant is referred to in FlyBase by the symbol Dmel\Met (CG1705, FBgn0002723).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -17.4797 -5.3429 -7.847415 -10.9068 -12.721304 -12.2942 -9.15287 -10.681576
    Affimetrix absolute value 4.326 5.21 5.222 4.949 5.097 4.942 5.362 4.886
    Affymetric present call in "x" number of chips 0 2 0 1 1 2 3 0
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein heterodimerization activity; juvenile hormone binding; protein homodimerization activity.
There is experimental evidence that it is involved in the biological process: regulation of transcription, DNA-dependent; regulation of developmental process.
23 alleles are reported.
The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: female germline cyst; organ system; gamete; organ system subdivision; lobula complex; adult segment; stage S9 oocyte; multi-cell-component structure; sensillum; region of integument.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Helix-loop-helix DNA-binding; Helix-loop-helix DNA-binding domain; PAC motif; PAS.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.
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