Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Mlc1
Flybase description The gene Myosin alkali light chain 1 is referred to in FlyBase by the symbol Dmel\Mlc1 (CG5596, FBgn0002772).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 34.3873 6.7072 3.471941 5.6494 3.044668 5.6787 18.74603 7.281903
    Affimetrix absolute value 13.496 10.282 9.938 10.875 10.351 11.039 12.768 11.04
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: ATPase activity, coupled.
There is experimental evidence that it is involved in the biological process: mesoderm development.
3 alleles are reported.
The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: EF-HAND 2; EF-hand-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of low expression.
Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.
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