Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name mnd
Flybase description The gene minidiscs is referred to in FlyBase by the symbol Dmel\mnd (CG3297, FBgn0002778).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -19.8564 -3.9934 -12.362985 -13.2013 -14.245701 -8.7879 -15.63948 -12.045054
    Affimetrix absolute value 4.139 5.637 4.566 4.686 4.939 5.427 4.64 4.67
    Affymetric present call in "x" number of chips 0 3 2 3 2 3 2 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: amino acid transmembrane transporter activity.
There is experimental evidence that it is involved in the biological process: leucine import.
51 alleles are reported.
The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: multicellular structure; anatomical structure; imaginal precursor; adult; embryonic/larval imaginal precursor; thoracic segment; organism; larval thorax; organ system subdivision; dorsal thoracic disc.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Amino acid permease domain; Amino acid/polyamine transporter I.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.
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