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Gene name | mus304 | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene mutagen-sensitive 304 is referred to in FlyBase by the symbol Dmel\mus304 (CG7347, FBgn0002901). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: ATP-dependent DNA helicase activity. There is experimental evidence that it is involved in the biological process: female meiosis chromosome segregation; reciprocal meiotic recombination; female meiosis; DNA repair; telomere maintenance; mitotic cell cycle G2/M transition DNA damage checkpoint; regulation of syncytial blastoderm mitotic cell cycle; DNA damage checkpoint. 15 alleles are reported. The phenotypes of these alleles are annotated with: cycle 13 embryo; wing disc; mitotic cell cycle; macrochaeta; cycle 12 embryo; mesothoracic tergum; cycle 14 embryo. It has one annotated transcript and one annotated polypeptide. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages. . |