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Gene name | mus309 | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene mutagen-sensitive 309 is referred to in FlyBase by the symbol Dmel\mus309 (CG6920, FBgn0002906). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: DNA strand annealing activity; Y-form DNA binding; ATP-dependent 3'-5' DNA helicase activity; DNA-dependent ATPase activity. There is experimental evidence that it is involved in the biological process: reciprocal meiotic recombination; DNA duplex unwinding; double-strand break repair via synthesis-dependent strand annealing; response to DNA damage stimulus; strand displacement; double-strand break repair; DNA synthesis involved in DNA repair; double-strand break repair via homologous recombination. 16 alleles are reported. The phenotype of these alleles is annotated with: wing disc. It has one annotated transcript and one annotated polypeptide. Protein features are: DEAD-like helicase; DNA helicase, ATP-dependent, RecQ type; DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; HRDC-like; HRDC-like, subdomain 1; Helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain; RQC domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. . |