Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name ndl
Flybase description The gene nudel is referred to in FlyBase by the symbol Dmel\ndl (CG10129, FBgn0002926).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -45.2301 -32.1499 -43.065644 -46.348 -59.580108 -61.4301 -57.69442 -46.595537
    Affimetrix absolute value 2.914 2.638 2.759 2.855 2.864 2.624 2.715 2.757
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: serine-type peptidase activity; peptidase activity; serine-type endopeptidase activity.
There is experimental evidence that it is involved in the biological process: eggshell chorion assembly; protein processing; dorsal/ventral axis specification; egg activation.
30 alleles are reported.
The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; vitelline membrane; egg; embryo.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Low-density lipoprotein (LDL) receptor class A repeat; Low-density lipoprotein (LDL) receptor class A, conserved site; Peptidase S1/S6, chymotrypsin/Hap; Peptidase S1/S6, chymotrypsin/Hap, active site; Peptidase S1A, nudel; Peptidase cysteine/serine, trypsin-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed in adult female stages.
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