Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name nos
Flybase description The gene nanos is referred to in FlyBase by the symbol Dmel\nos (CG5637, FBgn0002962).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -29.3338 -29.5544 -37.967256 -58.494 -59.809092 -61.8347 -54.46284 -43.841349
    Affimetrix absolute value 3.555 2.746 2.948 2.538 2.892 2.613 2.791 2.788
    Affymetric present call in "x" number of chips 1 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: germ-line stem cell maintenance; female meiosis chromosome segregation; dendrite morphogenesis; negative regulation of apoptosis; oogenesis; germ cell development; spermatogenesis.
266 alleles are reported.
The phenotypes of these alleles are annotated with 44 unique terms, many of which group under: embryonic abdomen; organ system; embryonic segment; organ system subdivision; germarium; cytoplasmic part; cephalopharyngeal skeleton; external compound sense organ; extended germ band embryo; adult segment.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Nanos/Xcat2; Zinc finger, CCHC-type; Zinc finger, nanos-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression.
Peak expression observed within 00-06 hour embryonic stages, in adult female stages.
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