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Gene name | numb | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene numb is referred to in FlyBase by the symbol Dmel\numb (CG3779, FBgn0002973). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence for 11 unique biological process terms, many of which group under: anatomical structure development; biological regulation; multicellular organismal process; regulation of biological process; localization; cell division; regulation of multicellular organismal development; organ development; cell fate commitment; regulation of developmental process. 84 alleles are reported. The phenotypes of these alleles are annotated with 210 unique terms, many of which group under: hypodermal muscle of larval abdomen; organ system; adult abdominal myoblast; larval abdominal segment 5; organ system subdivision; A1-7 oblique muscle; embryonic/larval neuron; abdominal segment 7; nervous system; A1-7 transverse muscle. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: NUMB domain; Numb/numb-like; Phosphotyrosine interaction domain; Pleckstrin homology-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 06-12 hour embryonic stages. . |