Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name ort
Flybase description The gene ora transientless is referred to in FlyBase by the symbol Dmel\ort (CG7411, FBgn0003011).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -60.0904 -37.5051 -44.799665 -64.1934 -66.888419 -78.081 -72.60765 -47.29863
    Affimetrix absolute value 2.502 2.393 2.769 2.393 2.7 2.277 2.397 2.701
    Affymetric present call in "x" number of chips 0 0 0 2 2 0 0 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: histamine-gated chloride channel activity.
There is experimental evidence that it is involved in the biological process: synaptic transmission; adult behavior; response to ether; response to toxin; thermotaxis.
19 alleles are reported.
The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: external compound sense organ; organ system subdivision; peripheral nervous system; nervous system; histaminergic neuron; rhabdomere; cell projection; cell part; cell; compound cell cluster organ.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Gamma-aminobutyric acid A receptor; Neurotransmitter-gated ion-channel; Neurotransmitter-gated ion-channel ligand-binding; Neurotransmitter-gated ion-channel transmembrane domain; Neurotransmitter-gated ion-channel, conserved site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of no expression detected.
Peak expression observed during late pupal stages.
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