Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name osk
Flybase description The gene oskar is referred to in FlyBase by the symbol Dmel\osk (CG10901, FBgn0003015).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -29.541 -41.2833 -59.836777 -69.8734 -80.229885 -78.7536 -88.68578 -63.527913
    Affimetrix absolute value 3.637 2.27 2.285 2.27 2.452 2.264 2.084 2.269
    Affymetric present call in "x" number of chips 2 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: hydrolase activity.
There is experimental evidence that it is involved in the biological process: regulation of mRNA stability; oocyte microtubule cytoskeleton polarization; visual learning; visual behavior; oogenesis; long-term memory; germ cell development; posterior abdomen determination; P granule organization.
118 alleles are reported.
The phenotypes of these alleles are annotated with 34 unique terms, many of which group under: embryonic abdomen; organ system; embryonic segment; multicellular structure; female germline cyst; non-connected developing system; cuticle; portion of tissue; abdominal segment 7; eo support cell; blastoderm embryo; cell part; embryonic abdominal segment 4; embryonic thorax; cephalopharyngeal skeleton; karyosome.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Esterase, SGNH hydrolase-type; Esterase, SGNH hydrolase-type, subgroup.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of no expression detected.
Peak expression observed within 00-06 hour embryonic stages, in adult female stages.
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