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Gene name | pbl | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene pebble is referred to in FlyBase by the symbol Dmel\pbl (CG8114, FBgn0003041). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: guanyl-nucleotide exchange factor activity. There is experimental evidence for 14 unique biological process terms, many of which group under: anatomical structure development; cell cycle; cell division; cell cycle process; cellular component organization or biogenesis; biological regulation; localization; regulation of developmental process; embryonic hindgut morphogenesis; mesoderm morphogenesis; cell adhesion; cytokinesis after meiosis; establishment of protein localization; regulation of multicellular organismal development. 43 alleles are reported. The phenotypes of these alleles are annotated with 24 unique terms, many of which group under: organ system subdivision; primordium; external compound sense organ; germ layer; cytoplasmic part; adult segment; organelle; ventral nerve cord primordium; presumptive embryonic/larval nervous system; adult mesothoracic segment. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: BRCT; Dbl homology (DH) domain; Pleckstrin homology-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages. . |