Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name polo
Flybase description The gene polo is referred to in FlyBase by the symbol Dmel\polo (CG12306, FBgn0003124).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -24.0175 -12.991 -13.229718 -13.7073 -17.129713 -8.2464 -33.08853 -14.612036
    Affimetrix absolute value 3.865 3.926 4.458 4.646 4.69 5.607 3.504 4.388
    Affymetric present call in "x" number of chips 0 1 1 3 1 3 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein serine/threonine kinase activity; protein kinase activity.
There is experimental evidence for 14 unique biological process terms, many of which group under: cell cycle; cellular component organization or biogenesis; M phase of meiotic cell cycle; cell cycle process; localization; meiosis II; cellular process involved in reproduction; anatomical structure development; biological regulation; pronuclear migration; organelle organization; regulation of multicellular organismal development.
41 alleles are reported.
The phenotypes of these alleles are annotated with 24 unique terms, many of which group under: organ system; multicellular structure; organelle; germarium; nucleus; nuclear part; cytoplasmic part; egg; organ system subdivision; spindle.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: POLO box duplicated domain; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression.
Peak expression observed within 00-12 hour embryonic stages, in adult female stages.
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