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Gene name | polo | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene polo is referred to in FlyBase by the symbol Dmel\polo (CG12306, FBgn0003124). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein serine/threonine kinase activity; protein kinase activity. There is experimental evidence for 14 unique biological process terms, many of which group under: cell cycle; cellular component organization or biogenesis; M phase of meiotic cell cycle; cell cycle process; localization; meiosis II; cellular process involved in reproduction; anatomical structure development; biological regulation; pronuclear migration; organelle organization; regulation of multicellular organismal development. 41 alleles are reported. The phenotypes of these alleles are annotated with 24 unique terms, many of which group under: organ system; multicellular structure; organelle; germarium; nucleus; nuclear part; cytoplasmic part; egg; organ system subdivision; spindle. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: POLO box duplicated domain; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages, in adult female stages. . |